艳妇乳肉豪妇荡乳AV无码福利,最新久久国产亚洲高清观看,91久久无码99精品高潮久,中文乱码字字幕在线第5页一,免费大片av手机看片不卡高清,91精品国产91久久久久久青草_精品国产亚洲人成在线观看_91国在线啪精品一区_国产一区二区三区在线免费_国产精品v欧美精品∨日韩_日韩欧美国产三级_国产三级精品三级在专区_国产精选第一页_欧美国产精品va在线观看 ,中文字幕一区二区三区精华液_亚洲欧美一区二区视频_麻花豆剧国产MV在视频_红桃AV一区二区三区在线无码AV ,国产欧美日本亚洲精品一5|99视频在线精品国自产拍亚瑟|国产色精品vr一区区三区|国产精品极品美女自在线观看免费|欧洲精品精美色视频在线观看

最近搜索:細(xì)胞培養(yǎng) 微生物學(xué) 分子生物 生物化學(xué)
首頁(yè)>>免疫學(xué)>>一抗>>低密度脂蛋白受體相關(guān)蛋白1抗體
低密度脂蛋白受體相關(guān)蛋白1抗體
  • 產(chǎn)品貨號(hào):
    BN40270R
  • 中文名稱(chēng):
    低密度脂蛋白受體相關(guān)蛋白1抗體
  • 英文名稱(chēng):
    Rabbit anti-LRP1 Polyclonal antibody
  • 品牌:
    Biorigin
  • 貨號(hào)

    產(chǎn)品規(guī)格

    售價(jià)

    備注

  • BN40270R-100ul

    100ul

    ¥2360.00

    交叉反應(yīng):Human(predicted:Sheep,Rabbit,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用:WB,IHC-P,ELISA

  • BN40270R-200ul

    200ul

    ¥3490.00

    交叉反應(yīng):Human(predicted:Sheep,Rabbit,Cow,Pig,Dog,Rat,Mouse) 推薦應(yīng)用:WB,IHC-P,ELISA

產(chǎn)品描述

英文名稱(chēng)LRP1
中文名稱(chēng)低密度脂蛋白受體相關(guān)蛋白1抗體
別    名A2MR; Alpha 2 macroglobulin receptor; alpha 2MR; APOER; Apolipoprotein E receptor; APR; CD 91; CD91; CD91 antigen; Low density lipoprotein receptor related protein 1; Low density lipoprotein related protein 1; LRP 1; LRP 515; LRP 85; LRP; LRP ICD; LRP1; LRP1 protein; LRP515.  
抗體來(lái)源Rabbit
克隆類(lèi)型Polyclonal
交叉反應(yīng)Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量85/515kDa
細(xì)胞定位細(xì)胞漿 細(xì)胞膜 
性    狀Liquid
濃    度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human LRP1:2501-2600/4544 <Extracellular>
亞    型IgG
純化方法affinity purified by Protein A
儲(chǔ) 存 液Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹Low density lipoprotein receptor-related protein (also known as low density LRP, LRP1, alpha-2-macroglobulin receptor or Apolipoprotein E receptor) is an endocytotic receptor that is involved both in endocytosis and in phagocytosis of apoptotic cells. It is required for early embryonic development, is involved in cellular lipid homeostasis, and may play a role in APP metabolism, kinase-dependent intracellular signalling, neuronal calcium signalling and neurotransmission. Low density LRP also plays a role in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha-2-macroglobulin), and is involved in the local metabolism of complexes of plasminogen activators and their endogenous ligands. Low density LPR is postulated to be one of the major players in host resistance to HIV. The precursor low density LRP molecule is cleaved post-translationally to form a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515), which remains non-covalently associated with LRP-85. Following cleavage, the intracellular domain (LPRICD) is present in both the cytoplasm and the nucleus.

Function:
Endocytic receptor involved in endocytosis and in phagocytosis of apoptotic cells. Required for early embryonic development. Involved in cellular lipid homeostasis. Involved in the plasma clearance of chylomicron remnants and activated LRPAP1 (alpha 2-macroglobulin), as well as the local metabolism of complexes between plasminogen activators and their endogenous inhibitors. May modulate cellular events, such as APP metabolism, kinase-dependent intracellular signaling, neuronal calcium signaling as well as neurotransmission. Functions as a receptor for Pseudomonas aeruginosa exotoxin A.

Subcellular Location:
Cell membrane. Membrane, coated pit and Cytoplasm. Nucleus. After cleavage, the intracellular domain (LRPICD) is detected both in the cytoplasm and in the nucleus.

Tissue Specificity:
Most abundant in liver, brain and lung.

Post-translational modifications:
Cleaved into a 85 kDa membrane-spanning subunit (LRP-85) and a 515 kDa large extracellular domain (LRP-515) that remains non-covalently associated. Gamma-secretase-dependent cleavage of LRP-85 releases the intracellular domain from the membrane.
The N-terminus is blocked.
Phosphorylated on serine and threonine residues.
Phosphorylated on tyrosine residues upon stimulation with PDGF. Tyrosine phosphorylation promotes interaction with SHC1.

Similarity:
Belongs to the LDLR family.
Contains 22 EGF-like domains.
Contains 31 LDL-receptor class A domains.
Contains 34 LDL-receptor class B repeats.

SWISS:
Q07954

Gene ID:
4035

Database links:

Entrez Gene: 4035 Human

Entrez Gene: 16971 Mouse

Entrez Gene: 100009547 Rabbit

Entrez Gene: 299858 Rat

Omim: 107770 Human

SwissProt: Q07954 Human

SwissProt: Q91ZX7 Mouse

Unigene: 162757 Human

Unigene: 271854 Mouse

Unigene: 22436 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications




















image.png

image.png

黑龙江省| 溧阳市| 沙洋县| 东阳市| 张家界市| 锡林郭勒盟| 越西县| 桂林市| 淮南市| 托克逊县| 湟中县| 湛江市| 武汉市| 会昌县| 胶南市| 香河县| 屏东县| 辰溪县| 泰州市| 金坛市| 荥阳市| 集安市| 仙桃市| 封丘县| 元阳县| 齐齐哈尔市| 临城县| 南川市| 彩票| 许昌市| 盈江县| 绥江县| 察哈| 珠海市| 罗田县| 图们市| 丹东市| 皮山县| 关岭| 淮安市| 洮南市|